The ins and outs of Mycobacterium tuberculosis drug susceptibility testing
نویسندگان
چکیده
منابع مشابه
Rapid diagnosis of Mycobacterium tuberculosis infection and drug susceptibility testing.
CONTEXT The global control of tuberculosis remains a challenge from the standpoint of diagnosis, detection of drug resistance, and treatment. This is an area of special concern to the health of women and children, particularly in regions of the world with high infant mortality rates and where women have limited access to health care. OBJECTIVE Because treatment can only be initiated when infe...
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Determination of the drug susceptibility of Mycobacterium tuberculosis by conventional methods using an agar-based medium may take 3 weeks or more to complete. On the other hand, results on positive cultures are generally available in 4 to 7 days with the radiometric (BACTEC, Johnston Laboratories, Towson, Md.) procedure. One disadvantage to the latter is the requirement to determine the quanti...
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In their recent article, Kristian Ängeby et al. (4) reported a novel test for drug susceptibility testing of Mycobacterium tuberculosis. However, it should be clarified that this method was previously published in 1989 (3) by Emil Kalfin, (National Institute for Lung Diseases, Sofia, Bulgaria) and Andreas Engibarov (National Center of Infectious and Parasitic Diseases, Sofia, Bulgaria). It is n...
متن کامل[External quality assessment of drug susceptibility testing for Mycobacterium tuberculosis].
OBJECTIVE The Committee for Mycobacterial Examinations has planned and implemented the third external quality assessment of drug susceptibility testing for Mycobacterium tuberculosis to the hospital and private laboratories. METHOD The Committee delivered 20 M. tuberculosis strains, exactly pairs of 10 strains, which were evaluated and standardized for the drug resistance pattern in the WHO/ ...
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The drug susceptibility testing performance of a broth-based method with microscopic reading of bacillary growth, the microscopic observation drug susceptibility (MODS) assay, was compared to that of the reference 7H10 agar method of proportion by using 53 isolates of Mycobacterium tuberculosis from persons at risk for multidrug-resistant TB. For isoniazid (0.1 micro g/ml) and rifampin (2.0 mic...
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ژورنال
عنوان ژورنال: Clinical Microbiology and Infection
سال: 2011
ISSN: 1198-743X
DOI: 10.1111/j.1469-0691.2011.03551.x